Why not fluvoxamine? He said of his study, This is the most extraordinary effect Ive seen in my 25 years practicing medicine.. Jan 17. 90,000 people will die in the next 3 weeks alone if we continue to ignore this drug that has caused no harm. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. There were no studies reported out so far where fluvoxamine made things worse or neutral. But they dont want their names used. The 5 observational studies is icing on the cake. Medium revoked my account for life. Instead, the government prefers to fund and promote new, proprietary drugs and vaccines, he says. Fluvoxamine has a systematic review and meta-analysis published in a top medical journal. A very short op-ed arguing for using fluvoxamine against COVID. of the 'intellectual dark web '" and allowed him to access a "large and receptive audience to his claims about a fluvoxamine conspiracy". Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. So you can address your OCD and if you get COVID, youll can up the dose. Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. It has enrolled only 130 people in the first month and is enrolling only 70 per week now. This document is a collection of evidence that highlights the glaring errors in our pandemic response. (Clayton Fox, Marty Makary, and Jeffrey Klausner). No more. I took it myself at that dosage and noticed zero side effects. We are ignoring the advice of the KOL group and doing nothing. We could have saved a lot of lives. Fluvoxamine has at least a 30% hospitalization and death benefit. They never make things worse so are safe to try. Everyone says "we need more data" to show fluvoxamine works for COVID. Even though an expert panel was overwhelmingly convinced in just one hour, hearing a very small subset of all the supporting evidence, the organizations that they belong to are taking their time. Here's why. This is quite stunning because the PK of the drug done at the Gates Foundation shows it only reaches 50% of the final concentration after 3 days. If not, they should at least acknowledge that fluvoxamine might be helpful by at least listing it as a possibility. Theyre finding alternative leaders to follow, Morris said. Steve Kirsch reported that doctors commonly say (of fluvoxamine), "This is the most powerful drug in my arsenal. I took it myself at that dosage and noticed zero side effects. Note that some of these articles are inaccurate. One of the drugs, Fluvoxamine, showed a 30 . Here are the key things you should know about fluvoxamine for COVID: It works. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. Hes now outlived his initial prognosis by several years. There is no evidence fluvoxamine is harmful and led to a worse outcome. My website www.skirsch.io has tons of info on fluvoxamine with all the links. Some people report mild nausea while on the drug (stops when stop the drug). The web value rate of skirsch.io is 2 . He's discovered a common medication that's highly effective in minimizing the impacts of COVID-19 - two studies have proven so. Kirsch and his wife, Michele, fund a charitable foundation, which by 2007 had given $75 million to different causes. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. But as Kirsch has clashed with the experts he initially surrounded himself with, hes grown increasingly close to others who share his perspectives on vaccineswho have, in turn, provided a large and receptive audience to his claims about a fluvoxamine conspiracy. It does not matter how many lives will be saved. This site requires JavaScript to run correctly. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. . Summary of key evidence. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. thinks it should be used (and that the NIH is wrong for waiting for more clinical trials). With little government funding available for such work, Kirsch founded the Covid-19 Early Treatment Fund (CETF), putting in $1 million of his own money and bringing in donations from Silicon Valley luminaries: the CETF website lists the foundations of Marc Benioff and Elon Musk as donors. Timing is everything with respect to outcomes. Summarizes the 5 observational studies, RCT, RWE, and some of the more interesting anecdotal data. You will be wired for 24 hours if you dont heed my advice. Steve Kirsch cut the check, which allowed Dr. Lenze to finish recruiting the 152 patients he needed for his trial. There are other non-prescription things you should always have on hand. So when a group of scientists applied for an EUA for fluvoxamine, what did the FDA do? I have all of these on hand and I load up on vitamin D3 every day. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. Then he hosted a superspreader event. The trials that were abandoned for futility werent getting events because the patients were given standard of care meds. When was the last time you saw a phase 3 fail where there was a 100% effect size in both an RCT and RWE study along with 4 independent observational trials all showing a positive effect, and there is clear mechanism of action where there is less than a 1% chance that it is not working (the SSRI's ordered their impact based on their Sigma activation which is 1 in 120 options), and where in every single case we are aware of the patient taking the drug reversed to normal in an average of 3 days? The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. Steve put in $1MM of his own money and . You will be wired for 24 hours if you dont heed my advice. There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. By Steve Kirsch Last updated: March 14, 2021 After I appeared on the60 Mi nut es story about fluvoxamine,I've received a lot of questions from people about how to treat COVID. Fluvoxamine - The backstory T he i nsi de st ory behi nd how f l uvoxami ne became a CO V I D t herapy By Steve Kirsch Last updated: June 3, 2021 . I couldnt tell I was on the drug. When I asked him why so many experts in the field disagreed with him, he alleged there were effortseither malicious or negligentto suppress evidence of cheap, effective covid treatments. Vaccine waitlist Dr. B collected data from millions. Steve Kirsch, current director of the Covid 19 Early Treatment fund is an MIT alumni who has made a career as a tech entrepreneur. The drug was FDA-approved more than 65 years ago. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. We need to keep people out of the hospital in the first place. His efforts became more focused on medical research when, in 2007, he was diagnosed with a rare blood cancer. The effect size is huge if the drug is given early right after symptoms start. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. This is a more comprehensive look at the key evidence supporting fluvoxamine: Hear from the doctors who did the studies directly as well as the Dean of Medicine at Emory University: List of the best evidence-based COVID treatment options. He is very smart, and he knows that he is very smart, and hesometimes he behaves like he thinks hes the smartest guy in the room, whether he is or isnt, he told me. The Lancet paper showed that if you were treated early enough and took the drug as prescribed (it only works if you take it), it was shown to reduce your chance of death by 12X making it far more effective than any other drug for COVID. In the second trial, it was shown to be 100% effective in long-haul COVID symptoms: None of the treated patients had any long-haul symptoms after 2 weeks compared to 60% of untreated patients having 1 or more of the 15 long-haul symptoms after two weeks, and 29% having 4 of more of the long haul symptoms after 2 weeks. This looks ominous, but it harmless. Kirsch told me that meta-analyses are a higher level of evidence than randomized controlled trials. When I responded that meta-analyses are only as good as the data they are based on, he said Id like to understand your source on that, because I cant find a source that says a phase 3 trial is greater evidence than a meta-analysis., When you characterize me, you need to say that Steve Kirsch doesn't go with majority votes on interpreting data.. Proxalutamide and fluvoxamine pushers and the early treatment grift. Months later, the site wont disclose how many doses it helped deliveror what it plans to do with user data. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. At the dosing for COVID (50mg BID x 14 days), there is a 1% chance of mild-nausea and because the dose is so low and the time it is taken is so short, and there are no psychotropic effects (which require more than 3 weeks of use; the psychotropic effects non-existent if you don't have depression or an anxiety disorder in the first place). , or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. Nobody who took the drug got sick at all, most all wanted to return to work within 3 days after starting treatment. So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. He says that Facebook took down one of his posts announcing his appearance on 60 Minutes. So how did a man once intent on furthering science become a source of misinformation that undermines the very research he funded? If you have trouble getting a prescription, perhaps you have OCD? Things took a final and dramatic turn once Kirsch started claiming the government was covering up vaccine deaths. . That was a lie. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. ICER Publishes Final Evidence Report and Policy Recommendations on Outpatient Treatments for COVID-19 - ICER. This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! Zero. He thinks # killed by vax could be anywhere between 0 and 150K people dead.. It is very important to educate doctors because most people rely on their doctors for advice. Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. But they dont want their names used. No more. Thanks for working tirelessly to help others. I couldnt tell I was on the drug. By the beginning of September, he was no longer the companys CEO, replaced by his co-founder, Marten Nelson. . Items included in the Television News search service. So the drug had no chance of working (since there were no events), so the trial was stopped for futility, NOT because the drug doesnt work. But while this effort was praiseworthy, Kirsch's predilection for oversimplifying and exaggerating led him to mislead. They all promised me when fluvoxamine passed Phase 3 trials, nearly everyone would use it. He has a BS/MS in Electrical Engineering and Computer Science from MIT. It was recommended back in January 2021 by a key opinion leader (KOL) panel to be used, but it took a year for, because they were rejected by 10 journals. But the confusion provided a fertile breeding ground for skeptics. YouTube , , , fluvoxamine, , , , , , , , , , has tons of info on fluvoxamine with all the links. Note that some of these articles are inaccurate. He immediately tweeted an offer to give anyone $1 million if they could win a debate with him about vaccine deaths. Quick Summary . Still, in the moment, his question threw me, and I stuttered. . Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. Jeffrey Morris, director of biostatistics at the University of Pennsylvania Perelman School of Medicine, has made debunking Kirschs claims something of a hobby. He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). While Kirsch had the final say in who received grants, no one I spoke with expressed concerns about what projects had been funded, or why. If you start later, doctors use higher dosages and compliance becomes a bigger problem. The NIH never did a risk benefit analysis of this drug. The NIH did nothing despite the fact the that NIH, FDA, CDC, and academic institutions participated in the panel. Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. He might be a good snake oil salesman., I experienced this myself when, on one call, we discussed several studies. . The NIH wrote a bullshit rejection because the FDA told them not to approve it. Doing something is better than nothing. Los Altos Hills resident Steve Kirsch funded research into the drug fluvoxamine as a treatment for COVID-19. Eventually, a press representative who was listening in, David Satterfield, unmuted his microphone to suggest we finish our conversation by email. Some people report mild nausea while on the drug (stops when stop the drug). Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. FDA official fluvoxamine rejection. After one or two conversations like that, I got tired of arguing, so I started avoiding his calls.. I have never heard of a case it didn't work. Or just depression about the vaccine mandates? In-patient use. Online. The next major effect is that that fluvoxamine activates the sigma-1 receptor. I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. Most recent articles first. We should be making decisions now based on the evidence on the table today. Dosage there is 30mg once a day. P-value was 10^-14 on that study (done by Dr. reach out to us at Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. They left their recommendation of fluvoxamine at NEUTRAL. One user reported dilated pupils and increased heart rate (which could be nerves about the dilated pupils). A very short op-ed arguing for using fluvoxamine against COVID. This is the gold standard of evidence based medicine, Article about the fluvoxamine rejection (The Verge). I fully expected both organizations to do absolutely nothing. You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. , a non-profit known as the nations drug pricing watchdog, did a review of the evidence and determined that fluvoxamine evidence is superior to Molnupiravir. Enter the email address you signed up with and we'll email you a reset link. Unfortunately, as Jeffrey Morris at UPenn points out, public health officials and scientists have done plenty to undermine their own authority, like claiming masks dont work, downplaying the natural immunity conveyed by previous covid infections, and not doing enough public communication about vaccine safety surveillance systems. The infectious disease scientists lied to me. There were IRB rules that required the 65 patients to be listed in the diagrams and charts. Its not about the science. Other drugs in this class include Prozac (fluoxetine), Zoloft (sertraline) and Paxil (paroxetine). NIH and WHO refuse to acknowledge it works since it will cause vaccine hesitancy if it is known that there is a drug that turns COVID into a mild disease. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. 1991-1992 to 7.1% in 2001-2002. It was approved by the FDA in 1994 and has been used in millions of patients worldwide. That was a big mistake because the original paper contained text related to earlier studies and the editors chopped it out. Fluvoxamine, created 37 years ago, is an inexpensive and widely available generic drug. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). ). 33. See this. Steven Todd Kirsch is an American entrepreneur. Try refreshing this page and updating them one Medicine today isnt about saving your life. Online Status. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. He is the inventor of the optical mouse and one of the first Internet search engines, Infoseek. So take the lowest likely effect size * 60% success rate and you are looking at an expected 45% reduction in death which is clearly better than a 0% reduction. The reason is pure corruption. including the very promising Fluvoxamine. This should be top news, but the press is ignoring this and attempt to write stories about it are killed by the editors. Is that really true? Once the Phase 2 result came out, it should have been embraced by doctors. Please read and agree to the disclaimer before watching this video.. Steve Kirsch On COVID Early Treatment and CensorshipSteve Kirsch is an entrepreneur and . After several failed attempts to stop the progression of his disease, he designed his own protocol for chemotherapy and doctor-shopped to find an oncologist who would give it to him. In October, the group reported that, while a few patients in the placebo group ended up in the hospital, none of the patients receiving fluvoxamine got sick enough to go. After one or two conversations like that, I got tired of arguing, so I started avoiding his calls, she said. This drug can save your life but you have to ask for it! As noted before, the repository has a link to the 1 hour serotonin lecture. So probability of successful Phase 3 can be estimated to be over 99.99% since there are tens of thousands of phase 3 studies. I have all of these on hand and I load up on vitamin D3 every day. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Saving the world has been a theme of Kirschs life for years. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for Read More The best COVID treatments for hospitalized patients Seven treatments for hospitalized COVID patients with very high success rates. Hes a genuinely good guy. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. After I ended the Zoom meeting, Satterfield called me to apologize for cutting us off. He felt like he in good conscience had to speak out about covid, and so he made the decision to separate himself from M10, says Char, who has known Kirsch since the 1980s. The sooner you start, the better the outcomes. . Independent appraisal committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes. The CDC has advised everyone to wear a mask. My crime? No long haul symptoms if you start the drug ASAP after first symptoms. The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. Some speaker, off camera, went on a . Hes very convincing. are all super cheap, effective, and available without a prescription. Why the FDA should grant an EUA for fluvoxamine immediately, a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients. If you cant get a prescription for COVID, then perhaps you have OCD? Medicine isnt about saving lives anymore. There are two ways Ive discovered that I may be able to save the world, he told an IEEE Spectrum reporter in 2000. He started 7 high tech companies, two with billion dollar market caps. Steve Kirsch is baffled. Here is the latest version. Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). Yeah, its possible, he told mehe also says that he has regularly seen Kirsch manipulate evidence so that it seems to support claims that are, in reality, baseless. I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. If you were drowning and we had no known standard of care to save your life and someone had a life preserver which worked 160 times in a row, should we throw them the life preserver or let them drown because we aren't absolutely sure the life preserver's benefit > risk (since just because it worked 160 times in a row and there is a 99.99% chance the effect didn't happen by chance, we could have just gotten lucky). Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. So there were too few events in the placebo group and they werent recruiting fast enough. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? They rejected the drug for insufficient evidence just like they always do for ivermectin. upcoming events, and more. By March 2020, hed settled on the idea of searching for covid treatments in the pre-existing pharmacopeia. The combined p value of the two studies is <.0001. Compulsive fiddling with your mask? We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. more time. I must admit that this is an anniversary that snuck It was recommended back in January 2021 by a key opinion leader (KOL) panel to be used, but it took a year for the KOL meeting notes to be published because they were rejected by 10 journals. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. fluvoxamine The fast, easy, safe, simple, low cost treatment for COVID that has worked 100% of the time to prevent hospitalization that nobody wants to talk about We now have a viable solution to reduce COVID hospitalization and mortality; Read More fluvoxamine Got COVID? Last Checked: 03/02/2023. From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). Get your prescription in advance of getting COVID. We now have a viable solution to reduce COVID hospitalization and mortality; Say you just got diagnosed with COVID. committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes, This site requires JavaScript to run correctly. Lack of action. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). 1. @stkirsch. All can merit a fluvoxamine prescription based on traditional diagnoses. Fluoxetine is just as effective. Dr. Eric Lenze: So the results were really pretty. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. Elsewhere he has said he began questioning vaccine safety after an unnamed Twitter follower told him several family members died after getting their shots. The other doctors aren't using it either because they don't know about it or fear doing anything not approved by the CDC for treating COVID. The ICER independent review showed fluvoxamine is more effective than Molnupiravir: Read this article I wrote about using fluvoxamine correctly for COVID. The NIH wrote a bullshit rejection because the FDA told them not to approve it. It never was. Telling the truth, he tweeted. I think we did rigorous reviews of proposals for research.. An MIT Technology Review investigation recently revealed how images of a minor and a tester on the toilet ended up on social media. Note that a total of 77 people got the drug, not 65. While YouTube has repeatedly taken down the full video of the DarkHorse episode, various clips have been watched over 4 million times, and the full audio remains available on Spotify. My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 1.15K 'This Has Cost Millions of Lives': Steve Kirsch on Suppression of Repurposed Drugs and a Spike in Deaths 5 Months After Vaccine Rollout American Thought Leaders AMERICAN THOUGHT LEADERS JAN JEKIELEK Show more Loading comments.

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